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Seizure reduction in TSC2‐mutant mouse model by an mTOR catalytic inhibitor

OBJECTIVE: Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder caused by autosomal‐dominant pathogenic variants in either the TSC1 or TSC2 gene, and it is characterized by hamartomas in multiple organs, such as skin, kidney, lung, and brain. These changes can result in epilepsy, learni...

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Detalles Bibliográficos
Autores principales:	Dhamne, Sameer C., Modi, Meera E., Gray, Audrey, Bonazzi, Simone, Craig, Lucas, Bainbridge, Elizabeth, Lalani, Lahin, Super, Chloe E., Schaeffer, Samantha, Capre, Ketthsy, Lubicka, Danuta, Liang, Guiqing, Burdette, Doug, McTighe, Stephanie M., Gurnani, Sarika, Vermudez, Sheryl Anne D., Curtis, Daniel, Wilson, Christopher J., Hameed, Mustafa Q., D'Amore, Angelica, Rotenberg, Alexander, Sahin, Mustafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578885/ https://www.ncbi.nlm.nih.gov/pubmed/37545094 http://dx.doi.org/10.1002/acn3.51868

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