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Glycolytic lactate production supports status epilepticus in experimental animals

OBJECTIVE: Status epilepticus (SE) requires rapid intervention to prevent cerebral injury and mortality. The ketogenic diet, which bypasses glycolysis, is a promising remedy for patients with refractory SE. We tested the role of glycolytic lactate production in sustaining SE. METHODS: Extracellular...

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Detalles Bibliográficos
Autores principales: Skwarzynska, Daria, Sun, Huayu, Kasprzak, Izabela, Sharma, Supriya, Williamson, John, Kapur, Jaideep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578888/
https://www.ncbi.nlm.nih.gov/pubmed/37632130
http://dx.doi.org/10.1002/acn3.51881

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