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Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress

AIMS: Enhancing SIRT1 activity exerts beneficial cardiovascular effects. In diabetes, plasma SIRT1 levels are reduced. We aimed to investigate the therapeutic potential of chronic recombinant murine SIRT1 (rmSIRT1) supplementation to alleviate endothelial and vascular dysfunction in diabetic mice (d...

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Detalles Bibliográficos
Autores principales:	Yang, Kangmin, Velagapudi, Srividya, Akhmedov, Alexander, Kraler, Simon, Lapikova-Bryhinska, Tetiana, Schmiady, Martin O, Wu, Xiaoping, Geng, Leiluo, Camici, Giovanni G, Xu, Aimin, Lüscher, Thomas F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578911/ https://www.ncbi.nlm.nih.gov/pubmed/37401647 http://dx.doi.org/10.1093/cvr/cvad102

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