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Amivantamab plus lazertinib in osimertinib-relapsed EGFR-mutant advanced non-small cell lung cancer: a phase 1 trial
Patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) often develop resistance to current standard third-generation EGFR tyrosine kinase inhibitors (TKIs); no targeted treatments are approved in the osimertinib-relapsed setting. In this open-label, dose-esc...
Autores principales: | Cho, Byoung Chul, Kim, Dong-Wan, Spira, Alexander I., Gomez, Jorge E., Haura, Eric B., Kim, Sang-We, Sanborn, Rachel E., Cho, Eun Kyung, Lee, Ki Hyeong, Minchom, Anna, Lee, Jong-Seok, Han, Ji-Youn, Nagasaka, Misako, Sabari, Joshua K., Ou, Sai-Hong Ignatius, Lorenzini, Patricia, Bauml, Joshua M., Curtin, Joshua C., Roshak, Amy, Gao, Grace, Xie, John, Thayu, Meena, Knoblauch, Roland E., Park, Keunchil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579096/ https://www.ncbi.nlm.nih.gov/pubmed/37710001 http://dx.doi.org/10.1038/s41591-023-02554-7 |
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