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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques

The main barrier to HIV cure is a persistent reservoir of latently infected CD4(+) T cells harboring replication-competent provirus that fuels rebound viremia upon antiretroviral therapy (ART) interruption. A leading approach to target this reservoir involves agents that reactivate latent HIV provir...

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Detalles Bibliográficos
Autores principales:	Dashti, Amir, Sukkestad, Sophia, Horner, Anna M., Neja, Margaret, Siddiqi, Zain, Waller, Chevaughn, Goldy, Jordan, Monroe, Dominique, Lin, Alice, Schoof, Nils, Singh, Vidisha, Mavigner, Maud, Lifson, Jeffrey D., Deleage, Claire, Tuyishime, Marina, Falcinelli, Shane D., King, Hannah A. D., Ke, Ruian, Mason, Rosemarie D., Archin, Nancie M., Dunham, Richard M., Safrit, Jeffrey T., Jean, Sherrie, Perelson, Alan S., Margolis, David M., Ferrari, Guido, Roederer, Mario, Silvestri, Guido, Chahroudi, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579098/ https://www.ncbi.nlm.nih.gov/pubmed/37783968 http://dx.doi.org/10.1038/s41591-023-02570-7

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