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Effect of tapered versus stable treatment with tumour necrosis factor inhibitors on disease flares in patients with rheumatoid arthritis in remission: a randomised, open label, non-inferiority trial
OBJECTIVES: Many patients with rheumatoid arthritis (RA) require treatment with tumour necrosis factor inhibitor (TNFi) to reach remission. It is debated whether tapering of TNFi to discontinuation should be considered in sustained remission. The aim of ARCTIC REWIND TNFi was to assess the effect of...
Autores principales: | Lillegraven, Siri, Paulshus Sundlisæter, Nina, Aga, Anna-Birgitte, Sexton, Joseph, Olsen, Inge Christoffer, Lexberg, Åse Stavland, Madland, Tor Magne, Fremstad, Hallvard, Høili, Christian A., Bakland, Gunnstein, Spada, Cristina, Haukeland, Hilde, Hansen, Inger Myrnes, Moholt, Ellen, Uhlig, Till, Solomon, Daniel H, van der Heijde, Désirée, Kvien, Tore K, Haavardsholm, Espen A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579188/ https://www.ncbi.nlm.nih.gov/pubmed/37607809 http://dx.doi.org/10.1136/ard-2023-224476 |
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