New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function

OBJECTIVES: Interleukin (IL) 17s cytokines are key drivers of inflammation that are functionally dysregulated in several human immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis (RA), psoriasis and inflammatory bowel disease (IBD). Targeting these cytokines has some therapeu...

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Detalles Bibliográficos
Autores principales: Saviano, Anella, Manosour, Adel Abo, Raucci, Federica, Merlino, Francesco, Marigliano, Noemi, Schettino, Anna, Wahid, Mussarat, Begum, Jenefa, Filer, Andrew, Manning, Julia E, Casillo, Gian Marco, Piccolo, Marialuisa, Ferraro, Maria Grazia, Marzano, Simona, Russomanno, Pasquale, Bellavita, Rosa, Irace, Carlo, Amato, Jussara, Alfaifi, Mohammed, Rimmer, Peter, Iqbal, Tariq, Pieretti, Stefano, Vellecco, Valentina, Caso, Francesco, Costa, Luisa, Giacomelli, Roberto, Scarpa, Raffaele, Cirino, Giuseppe, Bucci, Mariarosaria, McGettrick, Helen M, Grieco, Paolo, Iqbal, Asif Jilani, Maione, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Spondyloarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579190/
https://www.ncbi.nlm.nih.gov/pubmed/37580108
http://dx.doi.org/10.1136/ard-2023-224479

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