Cargando…

Impact of trifluoromethyl and sulfonyl groups on the biological activity of novel aryl-urea derivatives: synthesis, in-vitro, in-silico and SAR studies

We designed and prepared a novel series of urea derivatives with/without sulfonyl group in their structures to investigate the impact of the sulfonyl group on the biological activity of the evaluated compounds. Antibacterial investigations indicated that derivatives 7, 8, 9, and 11 had the most anti...

Descripción completa

Detalles Bibliográficos
Autores principales: Sroor, Farid M., Mahrous, Karima F., El-Kader, Heba A. M. Abd, Othman, Abdelmageed M., Ibrahim, Nada S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579241/
https://www.ncbi.nlm.nih.gov/pubmed/37845243
http://dx.doi.org/10.1038/s41598-023-44753-9

Ejemplares similares