Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

High-grade serous ovarian carcinoma (HGSOC) is characterised by poor outcome and extreme chromosome instability (CIN). Therapies targeting centrosome amplification (CA), a key mediator of chromosome missegregation, may have significant clinical utility in HGSOC. However, the prevalence of CA in HGSO...

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Detalles Bibliográficos
Autores principales: Sauer, Carolin M., Hall, James A., Couturier, Dominique-Laurent, Bradley, Thomas, Piskorz, Anna M., Griffiths, Jacob, Sawle, Ashley, Eldridge, Matthew D., Smith, Philip, Hosking, Karen, Reinius, Marika A. V., Morrill Gavarró, Lena, Mes-Masson, Anne-Marie, Ennis, Darren, Millan, David, Hoyle, Aoisha, McNeish, Iain A., Jimenez-Linan, Mercedes, Martins, Filipe Correia, Tischer, Julia, Vias, Maria, Brenton, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579337/
https://www.ncbi.nlm.nih.gov/pubmed/37845213
http://dx.doi.org/10.1038/s41467-023-41840-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579337/
https://www.ncbi.nlm.nih.gov/pubmed/37845213
http://dx.doi.org/10.1038/s41467-023-41840-3

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