An automated single-molecule FRET platform for high-content, multiwell plate screening of biomolecular conformations and dynamics

Single-molecule FRET (smFRET) has become a versatile tool for probing the structure and functional dynamics of biomolecular systems, and is extensively used to address questions ranging from biomolecular folding to drug discovery. Confocal smFRET measurements are amongst the widely used smFRET assay...

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Detalles Bibliográficos
Autores principales: Hartmann, Andreas, Sreenivasa, Koushik, Schenkel, Mathias, Chamachi, Neharika, Schake, Philipp, Krainer, Georg, Schlierf, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579363/
https://www.ncbi.nlm.nih.gov/pubmed/37845199
http://dx.doi.org/10.1038/s41467-023-42232-3

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