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Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling
In nervous system development, disease, and injury, neurons undergo programmed cell death, leaving behind cell corpses that are removed by phagocytic glia. Altered glial phagocytosis has been implicated in several neurological diseases including Alzheimer’s disease. To untangle the links between gli...
Autores principales: | Elguero, Johnny E., Liu, Guangmei, Tiemeyer, Katherine, Bandyadka, Shruthi, Gandevia, Heena, Duro, Lauren, Yan, Zhenhao, McCall, Kimberly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579427/ https://www.ncbi.nlm.nih.gov/pubmed/37854687 http://dx.doi.org/10.1016/j.isci.2023.108052 |
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