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Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling

In nervous system development, disease, and injury, neurons undergo programmed cell death, leaving behind cell corpses that are removed by phagocytic glia. Altered glial phagocytosis has been implicated in several neurological diseases including Alzheimer’s disease. To untangle the links between gli...

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Detalles Bibliográficos
Autores principales: Elguero, Johnny E., Liu, Guangmei, Tiemeyer, Katherine, Bandyadka, Shruthi, Gandevia, Heena, Duro, Lauren, Yan, Zhenhao, McCall, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579427/
https://www.ncbi.nlm.nih.gov/pubmed/37854687
http://dx.doi.org/10.1016/j.isci.2023.108052

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