Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23(ahl)

Mouse studies continue to help elaborate upon the genetic landscape of mammalian disease and the underlying molecular mechanisms. Here, we have investigated an Embigin(tm1b) allele maintained on a standard C57BL/6N background and on a co-isogenic C57BL/6N background in which the Cdh23(ahl) allele ha...

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Detalles Bibliográficos
Autores principales: Newton, Sherylanne, Aguilar, Carlos, Bunton-Stasyshyn, Rosie K., Flook, Marisa, Stewart, Michelle, Marcotti, Walter, Brown, Steve, Bowl, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579432/
https://www.ncbi.nlm.nih.gov/pubmed/37854703
http://dx.doi.org/10.1016/j.isci.2023.108056

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