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Multi-task learning for predicting synergistic drug combinations based on auto-encoding multi-relational graphs

Combinatorial drug therapy is a promising approach for treating complex diseases by combining drugs with synergistic effects. However, predicting effective drug combinations is challenging due to the complexity of biological systems and the limited understanding of pathophysiological mechanisms and...

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Detalles Bibliográficos
Autores principales:	Shan, Wenyu, Shen, Cong, Luo, Lingyun, Ding, Pingjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579440/ https://www.ncbi.nlm.nih.gov/pubmed/37854693 http://dx.doi.org/10.1016/j.isci.2023.108020

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