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Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8(+) T cells

OBJECTIVE: Roseburia intestinalis is a probiotic species that can suppress intestinal inflammation by producing metabolites. We aimed to study the role of R. intestinalis in colorectal tumourigenesis and immunotherapy. DESIGN: R. intestinalis abundance was evaluated in stools of patients with colore...

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Detalles Bibliográficos
Autores principales:	Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph JY, Wong, Sunny H, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Gut Microbiota
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579466/ https://www.ncbi.nlm.nih.gov/pubmed/37491158 http://dx.doi.org/10.1136/gutjnl-2023-330291

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