Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro

OBJECTIVE: Exhausted hepatitis B virus (HBV)-specific CD8 T cells in chronic HBV infection are broadly heterogeneous. Characterisation of their functional impairment may allow to distinguish patients with different capacity to control infection and reconstitute antiviral function. DESIGN: HBV dextra...

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Detalles Bibliográficos
Autores principales: Rossi, Marzia, Vecchi, Andrea, Tiezzi, Camilla, Barili, Valeria, Fisicaro, Paola, Penna, Amalia, Montali, Ilaria, Daffis, Stephane, Fletcher, Simon P, Gaggar, Anuj, Medley, Jonathan, Graupe, Michael, Lad, Latesh, Loglio, Alessandro, Soffredini, Roberta, Borghi, Marta, Pollicino, Teresa, Musolino, Cristina, Alfieri, Arianna, Brillo, Federica, Laccabue, Diletta, Massari, Marco, Boarini, Chiara, Abbati, Gianluca, Pedrazzi, Giuseppe, Missale, Gabriele, Lampertico, Pietro, Ferrari, Carlo, Boni, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579518/
https://www.ncbi.nlm.nih.gov/pubmed/36717219
http://dx.doi.org/10.1136/gutjnl-2022-327202

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