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Angiopoietin-2 binds to multiple interactive sites within von Willebrand factor

BACKGROUND: Biosynthesis of von Willebrand factor (VWF) in endothelial cells drives the formation of storage-organelles known as Weibel-Palade bodies (WPBs). WPBs also contain several other proteins, including angiopoietin-2 (Ang-2). OBJECTIVES: At present, the molecular basis of the VWF–Ang-2 inter...

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Detalles Bibliográficos
Autores principales:	Texier, Alexis, Lenting, Peter J., Denis, Cécile V., Roullet, Stéphanie, Christophe, Olivier D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579536/ https://www.ncbi.nlm.nih.gov/pubmed/37854453 http://dx.doi.org/10.1016/j.rpth.2023.102204

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