Uncovering the neuroprotective effect of vitamin B12 in pneumococcal meningitis: insights into its pleiotropic mode of action at the transcriptional level

BACKGROUND: The interplay between bacterial virulence factors and the host innate immune response in pneumococcal meningitis (PM) can result in uncontrolled neuroinflammation, which is known to induce apoptotic death of progenitor cells and post-mitotic neurons in the hippocampal dentate gyrus, resu...

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Detalles Bibliográficos
Autores principales: Cassiano, Larissa Marcely Gomes, Oliveira, Marina da Silva, de Queiroz, Karina Barbosa, Amancio, Alice Muglia Thomaz da Silva, Salim, Anna Christina de Matos, Fernandes, Gabriel da Rocha, Carneiro, Cláudia Martins, Coimbra, Roney Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579599/
https://www.ncbi.nlm.nih.gov/pubmed/37854591
http://dx.doi.org/10.3389/fimmu.2023.1250055

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