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Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia

We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory finding...

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Autores principales: Hatsukawa, Hiroatsu, Ishikawa, Masaaki, Hirai, Tomoyuki, Endo, Kazuo, Saito, Emiko, Matsumoto, Hirotaka, Okazaki, Kouya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579627/
https://www.ncbi.nlm.nih.gov/pubmed/37854459
http://dx.doi.org/10.1002/rcr2.1236
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author Hatsukawa, Hiroatsu
Ishikawa, Masaaki
Hirai, Tomoyuki
Endo, Kazuo
Saito, Emiko
Matsumoto, Hirotaka
Okazaki, Kouya
author_facet Hatsukawa, Hiroatsu
Ishikawa, Masaaki
Hirai, Tomoyuki
Endo, Kazuo
Saito, Emiko
Matsumoto, Hirotaka
Okazaki, Kouya
author_sort Hatsukawa, Hiroatsu
collection PubMed
description We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory findings, and/or eosinophilia detected in bronchoalveolar lavage. All patients were referred to otolaryngologists before undergoing oral corticosteroid treatment for CEP. Ten CEP cases visited to otolaryngologists. All cases showed bilateral sinonasal inflammation in computed tomography (CT), indicating comorbid CRS. Nasal polyps (NPs) were observed in 50% of patients on endoscopy. Eighty percent of patients were diagnosed with eosinophilic CRS. In blood eosinophil levels and the mucosal eosinophil count, there were no significant differences between CRS without and with NPs. In Lund–Mackay CT total scores, among‐individual variability was observed in CRS with NPs. The collaboration revealed blood/sinonasal eosinophilia and the variability in Lund–Mackay CT total scores as remarkable findings about the comorbid CRS.
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spelling pubmed-105796272023-10-18 Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia Hatsukawa, Hiroatsu Ishikawa, Masaaki Hirai, Tomoyuki Endo, Kazuo Saito, Emiko Matsumoto, Hirotaka Okazaki, Kouya Respirol Case Rep Case Series We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory findings, and/or eosinophilia detected in bronchoalveolar lavage. All patients were referred to otolaryngologists before undergoing oral corticosteroid treatment for CEP. Ten CEP cases visited to otolaryngologists. All cases showed bilateral sinonasal inflammation in computed tomography (CT), indicating comorbid CRS. Nasal polyps (NPs) were observed in 50% of patients on endoscopy. Eighty percent of patients were diagnosed with eosinophilic CRS. In blood eosinophil levels and the mucosal eosinophil count, there were no significant differences between CRS without and with NPs. In Lund–Mackay CT total scores, among‐individual variability was observed in CRS with NPs. The collaboration revealed blood/sinonasal eosinophilia and the variability in Lund–Mackay CT total scores as remarkable findings about the comorbid CRS. John Wiley & Sons, Ltd 2023-10-16 /pmc/articles/PMC10579627/ /pubmed/37854459 http://dx.doi.org/10.1002/rcr2.1236 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Hatsukawa, Hiroatsu
Ishikawa, Masaaki
Hirai, Tomoyuki
Endo, Kazuo
Saito, Emiko
Matsumoto, Hirotaka
Okazaki, Kouya
Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title_full Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title_fullStr Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title_full_unstemmed Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title_short Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
title_sort comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579627/
https://www.ncbi.nlm.nih.gov/pubmed/37854459
http://dx.doi.org/10.1002/rcr2.1236
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