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Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia
We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory finding...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579627/ https://www.ncbi.nlm.nih.gov/pubmed/37854459 http://dx.doi.org/10.1002/rcr2.1236 |
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author | Hatsukawa, Hiroatsu Ishikawa, Masaaki Hirai, Tomoyuki Endo, Kazuo Saito, Emiko Matsumoto, Hirotaka Okazaki, Kouya |
author_facet | Hatsukawa, Hiroatsu Ishikawa, Masaaki Hirai, Tomoyuki Endo, Kazuo Saito, Emiko Matsumoto, Hirotaka Okazaki, Kouya |
author_sort | Hatsukawa, Hiroatsu |
collection | PubMed |
description | We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory findings, and/or eosinophilia detected in bronchoalveolar lavage. All patients were referred to otolaryngologists before undergoing oral corticosteroid treatment for CEP. Ten CEP cases visited to otolaryngologists. All cases showed bilateral sinonasal inflammation in computed tomography (CT), indicating comorbid CRS. Nasal polyps (NPs) were observed in 50% of patients on endoscopy. Eighty percent of patients were diagnosed with eosinophilic CRS. In blood eosinophil levels and the mucosal eosinophil count, there were no significant differences between CRS without and with NPs. In Lund–Mackay CT total scores, among‐individual variability was observed in CRS with NPs. The collaboration revealed blood/sinonasal eosinophilia and the variability in Lund–Mackay CT total scores as remarkable findings about the comorbid CRS. |
format | Online Article Text |
id | pubmed-10579627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-105796272023-10-18 Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia Hatsukawa, Hiroatsu Ishikawa, Masaaki Hirai, Tomoyuki Endo, Kazuo Saito, Emiko Matsumoto, Hirotaka Okazaki, Kouya Respirol Case Rep Case Series We aimed to elucidate details of comorbid chronic rhinosinusitis (CRS) in chronic eosinophilic pneumonia (CEP) under the collaboration between otolaryngologists and pulmonologists in a prospective study. The CEP diagnosis was performed by pulmonologists based on clinical symptoms, laboratory findings, and/or eosinophilia detected in bronchoalveolar lavage. All patients were referred to otolaryngologists before undergoing oral corticosteroid treatment for CEP. Ten CEP cases visited to otolaryngologists. All cases showed bilateral sinonasal inflammation in computed tomography (CT), indicating comorbid CRS. Nasal polyps (NPs) were observed in 50% of patients on endoscopy. Eighty percent of patients were diagnosed with eosinophilic CRS. In blood eosinophil levels and the mucosal eosinophil count, there were no significant differences between CRS without and with NPs. In Lund–Mackay CT total scores, among‐individual variability was observed in CRS with NPs. The collaboration revealed blood/sinonasal eosinophilia and the variability in Lund–Mackay CT total scores as remarkable findings about the comorbid CRS. John Wiley & Sons, Ltd 2023-10-16 /pmc/articles/PMC10579627/ /pubmed/37854459 http://dx.doi.org/10.1002/rcr2.1236 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Hatsukawa, Hiroatsu Ishikawa, Masaaki Hirai, Tomoyuki Endo, Kazuo Saito, Emiko Matsumoto, Hirotaka Okazaki, Kouya Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title | Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title_full | Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title_fullStr | Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title_full_unstemmed | Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title_short | Comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
title_sort | comorbidity of eosinophilic chronic rhinosinusitis in chronic eosinophilic pneumonia |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579627/ https://www.ncbi.nlm.nih.gov/pubmed/37854459 http://dx.doi.org/10.1002/rcr2.1236 |
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