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Preventing the onset of depressive disorders in low-and middle-income countries: An overview

Depressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the...

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Autor principal: Cuijpers, Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579668/
https://www.ncbi.nlm.nih.gov/pubmed/37854437
http://dx.doi.org/10.1017/gmh.2023.22
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author Cuijpers, Pim
author_facet Cuijpers, Pim
author_sort Cuijpers, Pim
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description Depressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the alternative ways to further reduce the disease burden of depressive disorders. In this paper, the results of a subgroup analysis of a previous meta-analysis on the effect of preventive interventions on the incidence of depressive disorders was undertaken. Only 6% of all trials examining the possibility to prevent the onset of major depression have been conducted in LMICs, and these studies find significantly smaller effects than those in high-income settings. It is too early, therefore, to consider implementing and disseminating preventive interventions in LMICS. However, in optimal conditions and assuming that evidence-based preventive interventions will be developed, investments should be made into treatment, universal, selective and indicated prevention, as well as in social institutions focusing on larger risk factors for mental health problems.
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spelling pubmed-105796682023-10-18 Preventing the onset of depressive disorders in low-and middle-income countries: An overview Cuijpers, Pim Glob Ment Health (Camb) Review Depressive disorders constitute an important and costly public health problem and worldwide most of the disease burden is suffered in low-and middle-income countries (LMICs). Treatments only have limited possibilities to reduce the disease burden of depressive disorders. Prevention may be one of the alternative ways to further reduce the disease burden of depressive disorders. In this paper, the results of a subgroup analysis of a previous meta-analysis on the effect of preventive interventions on the incidence of depressive disorders was undertaken. Only 6% of all trials examining the possibility to prevent the onset of major depression have been conducted in LMICs, and these studies find significantly smaller effects than those in high-income settings. It is too early, therefore, to consider implementing and disseminating preventive interventions in LMICS. However, in optimal conditions and assuming that evidence-based preventive interventions will be developed, investments should be made into treatment, universal, selective and indicated prevention, as well as in social institutions focusing on larger risk factors for mental health problems. Cambridge University Press 2023-05-16 /pmc/articles/PMC10579668/ /pubmed/37854437 http://dx.doi.org/10.1017/gmh.2023.22 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Review
Cuijpers, Pim
Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_full Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_fullStr Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_full_unstemmed Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_short Preventing the onset of depressive disorders in low-and middle-income countries: An overview
title_sort preventing the onset of depressive disorders in low-and middle-income countries: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579668/
https://www.ncbi.nlm.nih.gov/pubmed/37854437
http://dx.doi.org/10.1017/gmh.2023.22
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