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Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report

Sjogren's syndrome is a rare chronic autoimmune disease characterised by dry eyes and dry mouth due to autoimmune destruction of the lacrimal and salivary glands, which can occur concurrently with other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or thyroidit...

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Autores principales: Khanal, Pitambar, Paudel, Sandip, Chapagain, Subodh, Thapa, Saurav, Gyawali, Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579740/
http://dx.doi.org/10.31729/jnma.8266
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author Khanal, Pitambar
Paudel, Sandip
Chapagain, Subodh
Thapa, Saurav
Gyawali, Madan
author_facet Khanal, Pitambar
Paudel, Sandip
Chapagain, Subodh
Thapa, Saurav
Gyawali, Madan
author_sort Khanal, Pitambar
collection PubMed
description Sjogren's syndrome is a rare chronic autoimmune disease characterised by dry eyes and dry mouth due to autoimmune destruction of the lacrimal and salivary glands, which can occur concurrently with other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or thyroiditis. It can lead to renal complications such as interstitial nephritis and glomerulonephritis, with distal/ type 1 renal tubular acidosis which may result in life-threatening electrolyte imbalance. We present a case of a 35-year-old female who presented with complaints of multiple episodes of muscle weakness. Type 1 renal tubular acidosis was discovered to be the cause of her symptoms which lead to the subsequent diagnosis of Sjogren's syndrome. This is rare presentation of Sjogren's syndrome, and it poses a challenge to diagnosis. Early detection and diagnosis of Sjogren's syndrome might be difficult due to existing diagnostic criteria, which contributes to a higher likelihood of missed diagnosis.
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spelling pubmed-105797402023-10-18 Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report Khanal, Pitambar Paudel, Sandip Chapagain, Subodh Thapa, Saurav Gyawali, Madan JNMA J Nepal Med Assoc Case Report Sjogren's syndrome is a rare chronic autoimmune disease characterised by dry eyes and dry mouth due to autoimmune destruction of the lacrimal and salivary glands, which can occur concurrently with other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or thyroiditis. It can lead to renal complications such as interstitial nephritis and glomerulonephritis, with distal/ type 1 renal tubular acidosis which may result in life-threatening electrolyte imbalance. We present a case of a 35-year-old female who presented with complaints of multiple episodes of muscle weakness. Type 1 renal tubular acidosis was discovered to be the cause of her symptoms which lead to the subsequent diagnosis of Sjogren's syndrome. This is rare presentation of Sjogren's syndrome, and it poses a challenge to diagnosis. Early detection and diagnosis of Sjogren's syndrome might be difficult due to existing diagnostic criteria, which contributes to a higher likelihood of missed diagnosis. Journal of the Nepal Medical Association 2023-09 2023-09-30 /pmc/articles/PMC10579740/ http://dx.doi.org/10.31729/jnma.8266 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khanal, Pitambar
Paudel, Sandip
Chapagain, Subodh
Thapa, Saurav
Gyawali, Madan
Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title_full Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title_fullStr Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title_full_unstemmed Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title_short Hypokalemic Paralysis Revealing Primary Sjogren's Syndrome: A Case Report
title_sort hypokalemic paralysis revealing primary sjogren's syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579740/
http://dx.doi.org/10.31729/jnma.8266
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