Characteristics and prognostic analysis of patients with detected KRAS mutations in resected lung adenocarcinomas by peptide nucleic acid-locked nucleic acid polymerase chain reaction (PNA-LNA PCR) clamp method

BACKGROUND: Kirsten rat sarcoma virus (KRAS) gene mutations are a type of driver mutation discovered in the 1980s, but for a long time no molecular targeted drugs were available for them. Recently, sotorasib was developed as a molecular targeted drug for KRAS mutations. It is therefore necessary to...

Descripción completa

Detalles Bibliográficos
Autores principales: Hashimoto, Tatsuya, Owada, Yoshihisa, Katagiri, Hiroshi, Yakuwa, Kazuhiro, Tyo, Katuya, Sugai, Mayu, Fuzimura, Itaru, Utsumi, Yu, Akiyama, Masachika, Nagashima, Hiromi, Terasaki, Hiroshi, Yanagawa, Naoki, Saito, Hajime, Sugai, Tamotsu, Maemondo, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579836/
https://www.ncbi.nlm.nih.gov/pubmed/37854155
http://dx.doi.org/10.21037/tlcr-23-15

Ejemplares similares

Ejemplares similares