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How the Unfolded Protein Response Is a Boon for Tumors and a Bane for the Immune System
The correct folding of proteins is essential for appropriate cell function and is tightly regulated within the endoplasmic reticulum (ER). Environmental challenges and cellular conditions disrupt ER homeostasis and induce ER stress, which adversely affect protein folding and activate the unfolded pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579845/ https://www.ncbi.nlm.nih.gov/pubmed/37067519 http://dx.doi.org/10.4049/immunohorizons.2200064 |