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Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis

The glycosyltransferase WaaG in Pseudomonas aeruginosa (PaWaaG) is involved in the synthesis of the core region of lipopolysaccharides. It is a promising target for developing adjuvants that could help in the uptake of antibiotics. Herein, we have determined structures of PaWaaG in complex with the...

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Detalles Bibliográficos
Autores principales: Scaletti, Emma R., Pettersson, Pontus, Patrick, Joan, Shilling, Patrick J., Westergren, Robert Gustafsson, Daley, Daniel O., Mäler, Lena, Widmalm, Göran, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579960/
https://www.ncbi.nlm.nih.gov/pubmed/37716703
http://dx.doi.org/10.1016/j.jbc.2023.105256