The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties

Inclusion body myositis (IBM) is an autoimmune and degenerative disorder of skeletal muscle. The B cell infiltrates in IBM muscle tissue are predominantly fully differentiated Ab-secreting plasma cells, with scarce naive or memory B cells. The role of this infiltrate in the disease pathology is not...

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Detalles Bibliográficos
Autores principales: Jiang, Roy, Roy, Bhaskar, Wu, Qian, Mohanty, Subhasis, Nowak, Richard J., Shaw, Albert C., Kleinstein, Steven H., O’Connor, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Clinical and Translational Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10579972/
https://www.ncbi.nlm.nih.gov/pubmed/37171806
http://dx.doi.org/10.4049/immunohorizons.2200078

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