Peripheral macrophages drive CNS disease in the Ndufs4(−/−) model of Leigh syndrome

Subacute necrotizing encephalopathy, or Leigh syndrome (LS), is the most common pediatric presentation of genetic mitochondrial disease. LS is a multi‐system disorder with severe neurologic, metabolic, and musculoskeletal symptoms. The presence of progressive, symmetric, and necrotizing lesions in t...

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Detalles Bibliográficos
Autores principales: Hanaford, Allison R., Khanna, Asheema, Truong, Vivian, James, Katerina, Chen, Yihan, Mulholland, Michael, Kayser, Bernhard, Liao, Ryan W., Sedensky, Margaret, Morgan, Phil, Andrew Baertsch, Nathan, Kalia, Vandana, Sarkar, Surojit, Johnson, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580015/
https://www.ncbi.nlm.nih.gov/pubmed/37552802
http://dx.doi.org/10.1111/bpa.13192

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