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Asymmetric synthesis of chiral (thio)chromanes and exploration on their structure–activity relationship in macrophages

A CuCl/(R,R)-Ph-BPE-catalyzed enantioselective hydroallylation of 2H-chromenes and 2H-thiochromenes with allylic phosphate electrophiles is developed, which enables highly efficient and atom-economical asymmetric access to a series of 4-allyl chromanes and thiochromanes in high yields (up to 91%) wi...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiao, Zhou, Qian, Zhou, Yue, Wang, Zihao, Wang, Jun, Wang, Mingfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580023/ https://www.ncbi.nlm.nih.gov/pubmed/37854489 http://dx.doi.org/10.1039/d3ra06428j

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