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Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation

• Chronic spinal cord stimulation effectiveness was evaluated in four PD patients. • Double blinded cross over evaluation was performed using subthreshold stimulation. • An open label evaluation with regular suprathreshold stimulation was also performed. • No statistically significant effect was pro...

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Autores principales: Carra, Rafael Bernhart, da Costa Capato, Tamine Teixeira, Menezes, Janaina Reis, Barbosa, Egberto Reis, Duarte, Kleber Paiva, Teixeira, Manoel Jacobsen, Cury, Rubens Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580045/
https://www.ncbi.nlm.nih.gov/pubmed/37854636
http://dx.doi.org/10.1016/j.prdoa.2023.100220
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author Carra, Rafael Bernhart
da Costa Capato, Tamine Teixeira
Menezes, Janaina Reis
Barbosa, Egberto Reis
Duarte, Kleber Paiva
Teixeira, Manoel Jacobsen
Cury, Rubens Gisbert
author_facet Carra, Rafael Bernhart
da Costa Capato, Tamine Teixeira
Menezes, Janaina Reis
Barbosa, Egberto Reis
Duarte, Kleber Paiva
Teixeira, Manoel Jacobsen
Cury, Rubens Gisbert
author_sort Carra, Rafael Bernhart
collection PubMed
description • Chronic spinal cord stimulation effectiveness was evaluated in four PD patients. • Double blinded cross over evaluation was performed using subthreshold stimulation. • An open label evaluation with regular suprathreshold stimulation was also performed. • No statistically significant effect was produced with either stimulation. • This study highlights the lack of strong clinical evidence supporting SCS for PD.
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spelling pubmed-105800452023-10-18 Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation Carra, Rafael Bernhart da Costa Capato, Tamine Teixeira Menezes, Janaina Reis Barbosa, Egberto Reis Duarte, Kleber Paiva Teixeira, Manoel Jacobsen Cury, Rubens Gisbert Clin Park Relat Disord Correspondence (including Letter to the Editor) • Chronic spinal cord stimulation effectiveness was evaluated in four PD patients. • Double blinded cross over evaluation was performed using subthreshold stimulation. • An open label evaluation with regular suprathreshold stimulation was also performed. • No statistically significant effect was produced with either stimulation. • This study highlights the lack of strong clinical evidence supporting SCS for PD. Elsevier 2023-10-06 /pmc/articles/PMC10580045/ /pubmed/37854636 http://dx.doi.org/10.1016/j.prdoa.2023.100220 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Correspondence (including Letter to the Editor)
Carra, Rafael Bernhart
da Costa Capato, Tamine Teixeira
Menezes, Janaina Reis
Barbosa, Egberto Reis
Duarte, Kleber Paiva
Teixeira, Manoel Jacobsen
Cury, Rubens Gisbert
Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title_full Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title_fullStr Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title_full_unstemmed Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title_short Long-term tonic spinal cord stimulation in advanced Parkinson’s disease: No effect from stimulation under placebo-controlled evaluation
title_sort long-term tonic spinal cord stimulation in advanced parkinson’s disease: no effect from stimulation under placebo-controlled evaluation
topic Correspondence (including Letter to the Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580045/
https://www.ncbi.nlm.nih.gov/pubmed/37854636
http://dx.doi.org/10.1016/j.prdoa.2023.100220
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