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A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria
[Image: see text] By illuminating key 6-azasteroid–protein interactions in both Mycobacterium tuberculosis (Mtb) and the closely related model organism Mycobacterium marinum (Mm), we sought to improve the antimycobacterial potency of 6-azasteroids and further our understanding of the mechanisms resp...
Autores principales: | Werman, Joshua M., Chen, Yu-Ching, Yuan, Tianao, Yang, Xinxin, Sampson, Nicole S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580313/ https://www.ncbi.nlm.nih.gov/pubmed/37774412 http://dx.doi.org/10.1021/acsinfecdis.3c00296 |
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