Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development

[Image: see text] Each year, approximately 50,000 children under 5 die as a result of diarrhea caused by Cryptosporidium parvum, a protozoan parasite. There are currently no effective drugs or vaccines available to cure or prevent Cryptosporidium infection, and there are limited tools for identifyin...

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Detalles Bibliográficos
Autores principales: Fenwick, Michael K., Reers, Alexandra R., Liu, Yi, Zigweid, Rachael, Sankaran, Banumathi, Shin, Janis, Hulverson, Matthew A., Hammerson, Bradley, Fernández Álvaro, Elena, Myler, Peter J., Kaushansky, Alexis, Van Voorhis, Wesley C., Fan, Erkang, Staker, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580320/
https://www.ncbi.nlm.nih.gov/pubmed/37722671
http://dx.doi.org/10.1021/acsinfecdis.3c00151

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