Successful Treatment of Hypoglycemia With Alpelisib in Pediatric Patients With PIK3CA-Related Overgrowth Spectrum

Activating mutations in the PIK3CA gene, causing phosphoinositide 3-kinase (PI3K) hyperactivation, are rare causes of hypoglycemia. We report the novel use of alpelisib (a PI3K inhibitor) for the treatment of hypoketotic, hypoinsulinemic hypoglycemia in 2 children with PIK3CA-related overgrowth spec...

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Detalles Bibliográficos
Autores principales: Nasomyont, Nat, Rutter, Meilan M, Backeljauw, Philippe F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580442/
https://www.ncbi.nlm.nih.gov/pubmed/37908459
http://dx.doi.org/10.1210/jcemcr/luad027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580442/
https://www.ncbi.nlm.nih.gov/pubmed/37908459
http://dx.doi.org/10.1210/jcemcr/luad027

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