Cargando…

Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis

Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, John, Senashova, Olga, Brinkerhoff, Brian, Lim, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580485/
https://www.ncbi.nlm.nih.gov/pubmed/37908995
http://dx.doi.org/10.1210/jcemcr/luad059
_version_ 1785121950707744768
author Sun, John
Senashova, Olga
Brinkerhoff, Brian
Lim, James
author_facet Sun, John
Senashova, Olga
Brinkerhoff, Brian
Lim, James
author_sort Sun, John
collection PubMed
description Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse or multiple organ failure, occurring over a rapid time frame. We describe an unusual case of a pheochromocytoma presenting with urinary frequency and subsequent shock and tumor hemorrhage following a urological procedure. Our patient was successfully managed with resuscitation and appropriate blood pressure control to stabilize hemodynamics prior to proceeding with open adrenalectomy. Furthermore, our patient presented initially with urinary symptoms, which has not been described as an initial presentation of pheochromocytoma. This case brings important learning points regarding unusually presenting pheochromocytomas and emergency management to improve patient survival.
format Online
Article
Text
id pubmed-10580485
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-105804852023-10-31 Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis Sun, John Senashova, Olga Brinkerhoff, Brian Lim, James JCEM Case Rep Case Report Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse or multiple organ failure, occurring over a rapid time frame. We describe an unusual case of a pheochromocytoma presenting with urinary frequency and subsequent shock and tumor hemorrhage following a urological procedure. Our patient was successfully managed with resuscitation and appropriate blood pressure control to stabilize hemodynamics prior to proceeding with open adrenalectomy. Furthermore, our patient presented initially with urinary symptoms, which has not been described as an initial presentation of pheochromocytoma. This case brings important learning points regarding unusually presenting pheochromocytomas and emergency management to improve patient survival. Oxford University Press 2023-07-27 /pmc/articles/PMC10580485/ /pubmed/37908995 http://dx.doi.org/10.1210/jcemcr/luad059 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sun, John
Senashova, Olga
Brinkerhoff, Brian
Lim, James
Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title_full Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title_fullStr Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title_full_unstemmed Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title_short Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
title_sort unusual pheochromocytoma presentation: from dysuria to catecholamine crisis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580485/
https://www.ncbi.nlm.nih.gov/pubmed/37908995
http://dx.doi.org/10.1210/jcemcr/luad059
work_keys_str_mv AT sunjohn unusualpheochromocytomapresentationfromdysuriatocatecholaminecrisis
AT senashovaolga unusualpheochromocytomapresentationfromdysuriatocatecholaminecrisis
AT brinkerhoffbrian unusualpheochromocytomapresentationfromdysuriatocatecholaminecrisis
AT limjames unusualpheochromocytomapresentationfromdysuriatocatecholaminecrisis