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Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis
Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580485/ https://www.ncbi.nlm.nih.gov/pubmed/37908995 http://dx.doi.org/10.1210/jcemcr/luad059 |
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author | Sun, John Senashova, Olga Brinkerhoff, Brian Lim, James |
author_facet | Sun, John Senashova, Olga Brinkerhoff, Brian Lim, James |
author_sort | Sun, John |
collection | PubMed |
description | Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse or multiple organ failure, occurring over a rapid time frame. We describe an unusual case of a pheochromocytoma presenting with urinary frequency and subsequent shock and tumor hemorrhage following a urological procedure. Our patient was successfully managed with resuscitation and appropriate blood pressure control to stabilize hemodynamics prior to proceeding with open adrenalectomy. Furthermore, our patient presented initially with urinary symptoms, which has not been described as an initial presentation of pheochromocytoma. This case brings important learning points regarding unusually presenting pheochromocytomas and emergency management to improve patient survival. |
format | Online Article Text |
id | pubmed-10580485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-105804852023-10-31 Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis Sun, John Senashova, Olga Brinkerhoff, Brian Lim, James JCEM Case Rep Case Report Pheochromocytomas are catecholamine-secreting tumors that can present as a surgical emergency, with a mortality rate as high as 15%. When these lesions present as a crisis, diagnosis and management can be very challenging, given the profound physiologic consequences, such as cardiovascular collapse or multiple organ failure, occurring over a rapid time frame. We describe an unusual case of a pheochromocytoma presenting with urinary frequency and subsequent shock and tumor hemorrhage following a urological procedure. Our patient was successfully managed with resuscitation and appropriate blood pressure control to stabilize hemodynamics prior to proceeding with open adrenalectomy. Furthermore, our patient presented initially with urinary symptoms, which has not been described as an initial presentation of pheochromocytoma. This case brings important learning points regarding unusually presenting pheochromocytomas and emergency management to improve patient survival. Oxford University Press 2023-07-27 /pmc/articles/PMC10580485/ /pubmed/37908995 http://dx.doi.org/10.1210/jcemcr/luad059 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sun, John Senashova, Olga Brinkerhoff, Brian Lim, James Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title | Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title_full | Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title_fullStr | Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title_full_unstemmed | Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title_short | Unusual Pheochromocytoma Presentation: From Dysuria to Catecholamine Crisis |
title_sort | unusual pheochromocytoma presentation: from dysuria to catecholamine crisis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580485/ https://www.ncbi.nlm.nih.gov/pubmed/37908995 http://dx.doi.org/10.1210/jcemcr/luad059 |
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