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Fusobacterium nucleatum facilitates proliferation and autophagy by activating miR-361-3p/NUDT1 axis through oxidative stress in hypopharyngeal squamous cell carcinoma

BACKGROUND: To investigate how Fusobacterium nucleatum (Fn) promotes oxidative stress and mediates proliferation and autophagy in hypopharyngeal squamous cell carcinoma (HPSCC). METHODS: The prognosis for 82 HPSCC cases was retrospectively analyzed. HPSCC cell line FaDu was co-cultured with Fn. Knoc...

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Detalles Bibliográficos
Autores principales: Lau, Hui-Ching, Yuan, Xiaohui, Huang, Huiying, Zhang, Ming, Hsueh, Chi-Yao, Gong, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580517/
https://www.ncbi.nlm.nih.gov/pubmed/37848855
http://dx.doi.org/10.1186/s12885-023-11439-4