A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report

BACKGROUND: Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. CASE PRESENTATION: In this report, we pr...

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Autores principales: Mardani, Parviz, Kamran, Hooman, Ghaderpanah, Rezvan, Geramizadeh, Bita, Fouladi, Damoun, Shahriarirad, Reza, Amirian, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580578/
https://www.ncbi.nlm.nih.gov/pubmed/37845684
http://dx.doi.org/10.1186/s13019-023-02389-w
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author Mardani, Parviz
Kamran, Hooman
Ghaderpanah, Rezvan
Geramizadeh, Bita
Fouladi, Damoun
Shahriarirad, Reza
Amirian, Armin
author_facet Mardani, Parviz
Kamran, Hooman
Ghaderpanah, Rezvan
Geramizadeh, Bita
Fouladi, Damoun
Shahriarirad, Reza
Amirian, Armin
author_sort Mardani, Parviz
collection PubMed
description BACKGROUND: Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. CASE PRESENTATION: In this report, we presented a 24-year-old patient with dyspnea, chest pain, nausea, and anorexia. A computed tomography scan revealed a giant, right-sided mass measuring about 190 × 150 × 140 mm. Chemotherapy was initiated for the patient, followed by thoracotomy. Histopathological evaluation revealed the nature of the mass to be an immature mediastinal teratoma. CONCLUSION: the incidence of immature mediastinal teratoma is uncommon, and due to its rarity, the diagnosis needs more profound evaluation studies such as radiological and pathological assessments. Immature teratomas are optimally treated by a combination of chemotherapy and complete resection.
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spelling pubmed-105805782023-10-18 A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report Mardani, Parviz Kamran, Hooman Ghaderpanah, Rezvan Geramizadeh, Bita Fouladi, Damoun Shahriarirad, Reza Amirian, Armin J Cardiothorac Surg Case Report BACKGROUND: Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma. CASE PRESENTATION: In this report, we presented a 24-year-old patient with dyspnea, chest pain, nausea, and anorexia. A computed tomography scan revealed a giant, right-sided mass measuring about 190 × 150 × 140 mm. Chemotherapy was initiated for the patient, followed by thoracotomy. Histopathological evaluation revealed the nature of the mass to be an immature mediastinal teratoma. CONCLUSION: the incidence of immature mediastinal teratoma is uncommon, and due to its rarity, the diagnosis needs more profound evaluation studies such as radiological and pathological assessments. Immature teratomas are optimally treated by a combination of chemotherapy and complete resection. BioMed Central 2023-10-16 /pmc/articles/PMC10580578/ /pubmed/37845684 http://dx.doi.org/10.1186/s13019-023-02389-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Mardani, Parviz
Kamran, Hooman
Ghaderpanah, Rezvan
Geramizadeh, Bita
Fouladi, Damoun
Shahriarirad, Reza
Amirian, Armin
A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title_full A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title_fullStr A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title_full_unstemmed A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title_short A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
title_sort massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580578/
https://www.ncbi.nlm.nih.gov/pubmed/37845684
http://dx.doi.org/10.1186/s13019-023-02389-w
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