Cargando…

Novel methodologies for host-microbe interactions and microbiome-targeted therapeutics in 3D organotypic skin models

BACKGROUND: Following descriptive studies on skin microbiota in health and disease, mechanistic studies on the interplay between skin and microbes are on the rise, for which experimental models are in great demand. Here, we present a novel methodology for microbial colonization of organotypic skin a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rikken, Gijs, Meesters, Luca D., Jansen, Patrick A. M., Rodijk-Olthuis, Diana, van Vlijmen-Willems, Ivonne M. J. J., Niehues, Hanna, Smits, Jos P. H., Oláh, Peter, Homey, Bernhard, Schalkwijk, Joost, Zeeuwen, Patrick L. J. M., van den Bogaard, Ellen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580606/ https://www.ncbi.nlm.nih.gov/pubmed/37849006 http://dx.doi.org/10.1186/s40168-023-01668-x

Ejemplares similares

Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis
por: Niehues, Hanna, et al.
Publicado: (2021)

Know your enemy: Unexpected, pervasive and persistent viral and bacterial contamination of primary cell cultures
por: Niehues, Hanna, et al.
Publicado: (2020)

Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models
por: Smits, Jos P. H., et al.
Publicado: (2017)

The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A
por: Smits, Jos P.H., et al.
Publicado: (2023)

OR5-002 – In vitro studies in Schnitzler’s syndrome
por: De Koning, HD, et al.
Publicado: (2013)

Genetically Programmed Differences in Epidermal Host Defense between Psoriasis and Atopic Dermatitis Patients
por: Zeeuwen, Patrick L. J. M., et al.
Publicado: (2008)

Carboxamide Derivatives Are Potential Therapeutic AHR Ligands for Restoring IL-4 Mediated Repression of Epidermal Differentiation Proteins
por: Rikken, Gijs, et al.
Publicado: (2022)

Skin microbiota in health and disease: From sequencing to biology
por: Ederveen, Thomas H. A., et al.
Publicado: (2020)

β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin
por: Jansen, Patrick A. M., et al.
Publicado: (2009)

Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin
por: van den Bogaard, Ellen H. J., et al.
Publicado: (2018)

CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application
por: Smits, Jos P.H., et al.
Publicado: (2021)

Microbe-host interplay in atopic dermatitis and psoriasis
por: Fyhrquist, Nanna, et al.
Publicado: (2019)

A generic workflow for Single Locus Sequence Typing (SLST) design and subspecies characterization of microbiota
por: Ederveen, Thomas H. A., et al.
Publicado: (2019)

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle
por: Oortveld, Merel A. W., et al.
Publicado: (2017)

Terminal keratinocyte differentiation in vitro is associated with a stable DNA methylome
por: Smits, Jos P. H., et al.
Publicado: (2020)

Vesicular hand eczema transcriptome analysis provides insights into its pathophysiology
por: Voorberg, Angelique N., et al.
Publicado: (2021)

A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes
por: Vos, Joost B, et al.
Publicado: (2006)

Microbiome dynamics of human epidermis following skin barrier disruption
por: Zeeuwen, Patrick LJM, et al.
Publicado: (2012)

Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice
por: Egging, David F., et al.
Publicado: (2008)

The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture
por: Di Blasio, S., et al.
Publicado: (2020)

Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats
por: Armour, John A. L., et al.
Publicado: (2007)

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation
por: van den Bogaard, Ellen, et al.
Publicado: (2015)

PW03-007 - NLRP3 genetic variants in Schnitzler’s syndrome
por: De Koning, HD, et al.
Publicado: (2013)

High phenylalanine concentrations induce demyelination and microglial activation in mouse cerebellar organotypic slices
por: Thau-Zuchman, Orli, et al.
Publicado: (2022)

Organotypic Modeling of the Tumor Landscape
por: Haykal, Maria M., et al.
Publicado: (2020)

Special review series on 3D organotypic culture models: Introduction and historical perspective
por: Hayden, Patrick J., et al.
Publicado: (2020)

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation
por: Kouwenhoven, Evelyn N, et al.
Publicado: (2015)

Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria
por: Jansen, Patrick A. M., et al.
Publicado: (2019)

Organotypic Epithelial Raft Cultures as a Three-Dimensional In Vitro Model of Merkel Cell Carcinoma
por: Temblador, Arturo, et al.
Publicado: (2022)

An Organotypic Microcosm for the Pancreatic Tumor Microenvironment
por: Lin, Miranda, et al.
Publicado: (2020)

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture
por: Chakrabarty, Sanjiban, et al.
Publicado: (2022)

mSphere of Influence: Engineering Microbes
por: McNamara, Patrick J.
Publicado: (2019)

Expression of fluorescent proteins in Lactobacillus rhamnosus to study host–microbe and microbe–microbe interactions
por: Spacova, Irina, et al.
Publicado: (2017)

Organotypic cultures as aging associated disease models
por: Sanchez, Martina M., et al.
Publicado: (2022)

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection
por: Hurtado de Mendoza, Tatiana, et al.
Publicado: (2011)

Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
por: Kaaijk, P., et al.
Publicado: (1996)

The aryl hydrocarbon receptor at the forefront of host‐microbe interactions in the skin: A perspective on current knowledge gaps and directions for future research and therapeutic applications
por: van den Bogaard, Ellen H., et al.
Publicado: (2021)

An organotypic oral mucosal infection model to study host-pathogen interactions
por: Gould, Samantha J, et al.
Publicado: (2023)

Organotypic Human Skin Cultures Incorporating Primary Melanocytes
por: Roth‐Carter, Quinn R., et al.
Publicado: (2022)

Correlation of in vitro infiltration with glioma histological type in organotypic brain slices
por: Palfi, S, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_s2rui7qlmuk1t8pc0sv06nljqb