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RORα overexpression reduced interleukin‐33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis

BACKGROUND: Retinoid acid receptor related orphan receptor α (RORα) is a nuclear receptor that along with other bioactive factors regulates cell proliferation, differentiation, and immunomodulation in vivo. AIMS: The objective of this study was to explore the function and mechanism of RORα in allerg...

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Detalles Bibliográficos
Autores principales: Yu, Wangbo, Du, Jingwei, Peng, Lijuan, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580702/
https://www.ncbi.nlm.nih.gov/pubmed/37904695
http://dx.doi.org/10.1002/iid3.1017