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Development and characterization of phage display-derived anti-toxin antibodies neutralizing TcdA and TcdB of Clostridioides difficile

TcdA and TcdB are known as the major virulence attributes of Clostridioides difficile. Hence, neutralizing the TcdA and TcdB activities can be considered as an efficient therapeutic approach against C. difficile infection (CDI). In this work, we utilized phage display technique to select single-chai...

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Detalles Bibliográficos
Autores principales:	Raeisi, Hamideh, Azimirad, Masoumeh, Asadzadeh Aghdaei, Hamid, Zarnani, Amir-Hassan, Abdolalizadeh, Jalal, Yadegar, Abbas, Zali, Mohammad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580902/ https://www.ncbi.nlm.nih.gov/pubmed/37668373 http://dx.doi.org/10.1128/spectrum.05310-22

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