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High selectivity of the hyperthermophilic subtilase propeptide domain toward inhibition of its cognate protease

Microbial extracellular subtilases are highly active proteolytic enzymes commonly used in commercial applications. These subtilases are synthesized in their inactive proform, which matures into the active protease under the control of the propeptide domain. In mesophilic bacterial prosubtilases, the...

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Detalles Bibliográficos
Autores principales: Bahun, Miha, Poklar Ulrih, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580911/
https://www.ncbi.nlm.nih.gov/pubmed/37655909
http://dx.doi.org/10.1128/spectrum.01487-23