Novel mechanism of hydrogen peroxide for promoting efficient natamycin synthesis in Streptomyces

The mechanism of regulation of natamycin biosynthesis by Streptomyces in response to oxidative stress is unclear. Here, we first show cholesterol oxidase SgnE, which catalyzes the formation of H(2)O(2) from sterols, triggered a series of redox-dependent interactions to stimulate natamycin production...

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Detalles Bibliográficos
Autores principales: Zong, Gongli, Cao, Guangxiang, Fu, Jiafang, Zhang, Peipei, Chen, Xi, Yan, Wenxiu, Xin, Lulu, Wang, Zhongxue, Xu, Yan, Zhang, Rongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580950/
https://www.ncbi.nlm.nih.gov/pubmed/37695060
http://dx.doi.org/10.1128/spectrum.00879-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580950/
https://www.ncbi.nlm.nih.gov/pubmed/37695060
http://dx.doi.org/10.1128/spectrum.00879-23

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