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Novel mechanism of hydrogen peroxide for promoting efficient natamycin synthesis in Streptomyces
The mechanism of regulation of natamycin biosynthesis by Streptomyces in response to oxidative stress is unclear. Here, we first show cholesterol oxidase SgnE, which catalyzes the formation of H(2)O(2) from sterols, triggered a series of redox-dependent interactions to stimulate natamycin production...
Autores principales: | Zong, Gongli, Cao, Guangxiang, Fu, Jiafang, Zhang, Peipei, Chen, Xi, Yan, Wenxiu, Xin, Lulu, Wang, Zhongxue, Xu, Yan, Zhang, Rongzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580950/ https://www.ncbi.nlm.nih.gov/pubmed/37695060 http://dx.doi.org/10.1128/spectrum.00879-23 |
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