Intra-host Trypanosoma cruzi strain dynamics shape disease progression: the missing link in Chagas disease pathogenesis

Chronic Chagasic cardiomyopathy develops years after infection in 20–40% of patients, but disease progression is poorly understood. Here, we assessed Trypanosoma cruzi parasite dynamics and pathogenesis over a 2.5-year period in naturally infected rhesus macaques. Individuals with better control of...

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Detalles Bibliográficos
Autores principales: Dumonteil, Eric, Desale, Hans, Tu, Weihong, Hernandez-Cuevas, Nora, Shroyer, Monica, Goff, Kelly, Marx, Preston A., Herrera, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581044/
https://www.ncbi.nlm.nih.gov/pubmed/37668388
http://dx.doi.org/10.1128/spectrum.04236-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581044/
https://www.ncbi.nlm.nih.gov/pubmed/37668388
http://dx.doi.org/10.1128/spectrum.04236-22

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