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La-related protein 4 is enriched in vaccinia virus factories and is required for efficient viral replication in primary human fibroblasts
In addition to the 3′-poly(A) tail, vaccinia virus mRNAs synthesized after viral DNA replication (post-replicative mRNAs) possess a 5′-poly(A) leader that confers a translational advantage in virally infected cells. These mRNAs are synthesized in viral factories, the cytoplasmic compartment where va...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581054/ https://www.ncbi.nlm.nih.gov/pubmed/37594266 http://dx.doi.org/10.1128/spectrum.01390-23 |