Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions

The flavivirus non-structural protein 1 (NS1) is secreted from infected cells into the circulation and the serum levels correlate with disease severity. The effect of secreted NS1 (sNS1) on non-infected mammalian immune cells is largely unknown. Here, we expressed recombinant sNS1 proteins of tick-b...

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Detalles Bibliográficos
Autores principales: Camarão, António A. R., Gern, Olivia Luise, Stegmann, Felix, Mulenge, Felix, Costa, Bibiana, Saremi, Babak, Jung, Klaus, Lepenies, Bernd, Kalinke, Ulrich, Steffen, Imke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581055/
https://www.ncbi.nlm.nih.gov/pubmed/37707204
http://dx.doi.org/10.1128/spectrum.02192-23

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