Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland

The syndrome of inappropriate ADH-secretion (SIADH) is a common cause of low sodium levels with diverse aetiology. Here, we report a case of a 41 years old male patient diagnosed with SIADH and a good response to Tolvaptan therapy. Of interest, as a potential unique cause, magnetic resonance imaging...

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Autores principales: Reinke, Lennart M., Seoudy, Anna Katharina, Gärtner, Friedericke, Rohmann, Nathalie, Schulte, Dominik M., Schreiber, Stefan, Jansen, Olav, Laudes, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581092/
https://www.ncbi.nlm.nih.gov/pubmed/37364592
http://dx.doi.org/10.1055/a-2093-1002
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author Reinke, Lennart M.
Seoudy, Anna Katharina
Gärtner, Friedericke
Rohmann, Nathalie
Schulte, Dominik M.
Schreiber, Stefan
Jansen, Olav
Laudes, Matthias
author_facet Reinke, Lennart M.
Seoudy, Anna Katharina
Gärtner, Friedericke
Rohmann, Nathalie
Schulte, Dominik M.
Schreiber, Stefan
Jansen, Olav
Laudes, Matthias
author_sort Reinke, Lennart M.
collection PubMed
description The syndrome of inappropriate ADH-secretion (SIADH) is a common cause of low sodium levels with diverse aetiology. Here, we report a case of a 41 years old male patient diagnosed with SIADH and a good response to Tolvaptan therapy. Of interest, as a potential unique cause, magnetic resonance imaging revealed a micronodular structure in the posterior pituitary, while no other common cause of SIADH could be identified. Hence, to the best of our knowledge, this is the first case of a Tolvaptan-responsive SIADH associated with a pituitary micronodular structure.
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spelling pubmed-105810922023-10-18 Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland Reinke, Lennart M. Seoudy, Anna Katharina Gärtner, Friedericke Rohmann, Nathalie Schulte, Dominik M. Schreiber, Stefan Jansen, Olav Laudes, Matthias Exp Clin Endocrinol Diabetes The syndrome of inappropriate ADH-secretion (SIADH) is a common cause of low sodium levels with diverse aetiology. Here, we report a case of a 41 years old male patient diagnosed with SIADH and a good response to Tolvaptan therapy. Of interest, as a potential unique cause, magnetic resonance imaging revealed a micronodular structure in the posterior pituitary, while no other common cause of SIADH could be identified. Hence, to the best of our knowledge, this is the first case of a Tolvaptan-responsive SIADH associated with a pituitary micronodular structure. Georg Thieme Verlag KG 2023-06-26 /pmc/articles/PMC10581092/ /pubmed/37364592 http://dx.doi.org/10.1055/a-2093-1002 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Reinke, Lennart M.
Seoudy, Anna Katharina
Gärtner, Friedericke
Rohmann, Nathalie
Schulte, Dominik M.
Schreiber, Stefan
Jansen, Olav
Laudes, Matthias
Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title_full Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title_fullStr Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title_full_unstemmed Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title_short Relapsing Syndrome of Inappropriate Antidiuretic Hormone Production Responding to Tolvaptan Treatment in a Patient With a Micronodular Formation of the Posterior Pituitary Gland
title_sort relapsing syndrome of inappropriate antidiuretic hormone production responding to tolvaptan treatment in a patient with a micronodular formation of the posterior pituitary gland
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581092/
https://www.ncbi.nlm.nih.gov/pubmed/37364592
http://dx.doi.org/10.1055/a-2093-1002
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