Cargando…

Genetic, vascular and amyloid components of cerebral blood flow in a preclinical population

Aging-related cognitive decline can be accelerated by a combination of genetic factors, cardiovascular and cerebrovascular dysfunction, and amyloid-β burden. Whereas cerebral blood flow (CBF) has been studied as a potential early biomarker of cognitive decline, its normal variability in healthy elde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Padrela, Beatriz E, Lorenzini, Luigi, Collij, Lyduine E, García, David Vállez, Coomans, Emma, Ingala, Silvia, Tomassen, Jori, Deckers, Quinten, Shekari, Mahnaz, de Geus, Eco JC, van de Giessen, Elsmarieke, Kate, Mara ten, Visser, Pieter Jelle, Barkhof, Frederik, Petr, Jan, den Braber, Anouk, Mutsaerts, Henk JMM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581242/ https://www.ncbi.nlm.nih.gov/pubmed/37231665 http://dx.doi.org/10.1177/0271678X231178993

Ejemplares similares

Regional associations of white matter hyperintensities and early cortical amyloid pathology
por: Lorenzini, Luigi, et al.
Publicado: (2022)

Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals
por: Ingala, Silvia, et al.
Publicado: (2021)

Genetically identical twins show comparable tau PET load and spatial distribution
por: Coomans, Emma M, et al.
Publicado: (2022)

Plasma biomarkers predict amyloid pathology in cognitively normal monozygotic twins after 10 years
por: den Braber, Anouk, et al.
Publicado: (2023)

Genetically identical twin-pair difference models support the amyloid cascade hypothesis
por: Coomans, Emma M, et al.
Publicado: (2023)

Performance of a [(18)F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia With Lewy Bodies
por: Coomans, Emma M., et al.
Publicado: (2023)

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score
por: Tomassen, Jori, et al.
Publicado: (2022)

White matter microstructure disruption in early stage amyloid pathology
por: Collij, Lyduine E., et al.
Publicado: (2021)

Reproducibility of 3 T APT‐CEST in Healthy Volunteers and Patients With Brain Glioma
por: Wamelink, Ivar J.H.G., et al.
Publicado: (2022)

Abnormal cerebrospinal fluid levels of amyloid and tau are associated with cognitive decline over time in cognitively normal older adults: A monozygotic twin study
por: Tomassen, Jori, et al.
Publicado: (2022)

Retinal layer thickness in preclinical Alzheimer's disease
por: van de Kreeke, Jacoba A., et al.
Publicado: (2019)

Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals
por: Lorenzini, Luigi, et al.
Publicado: (2023)

Clinical outcomes up to 9 years after [(18)F]flutemetamol amyloid-PET in a symptomatic memory clinic population
por: Collij, Lyduine E., et al.
Publicado: (2023)

Quantification of amyloid PET for future clinical use: a state-of-the-art review
por: Pemberton, Hugh G., et al.
Publicado: (2022)

Assessing Amyloid Pathology in Cognitively Normal Subjects Using (18)F-Flutemetamol PET: Comparing Visual Reads and Quantitative Methods
por: Collij, Lyduine E., et al.
Publicado: (2019)

Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals
por: Collij, Lyduine E., et al.
Publicado: (2021)

Associations of Brain Pathology Cognitive and Physical Markers With Age in Cognitively Normal Individuals Aged 60–102 Years
por: Legdeur, Nienke, et al.
Publicado: (2019)

Gray matter network properties show distinct associations with CSF p-tau 181 levels and amyloid status in individuals without dementia
por: Luigi, Lorenzini, et al.
Publicado: (2022)

Ocular biomarkers for cognitive impairment in nonagenarians; a prospective cross-sectional study
por: van de Kreeke, Jacoba A., et al.
Publicado: (2020)

Optical coherence tomography angiography in preclinical Alzheimer’s disease
por: van de Kreeke, Jacoba Alida, et al.
Publicado: (2020)

Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer’s disease and neurodegeneration stratified by sex
por: Cumplido-Mayoral, Irene, et al.
Publicado: (2023)

The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact
por: Collij, Lyduine E., et al.
Publicado: (2023)

Longitudinal retinal layer changes in preclinical Alzheimer’s disease
por: van de Kreeke, Jacoba A., et al.
Publicado: (2020)

Gray matter hypoperfusion is a late pathological event in the course of Alzheimer’s disease
por: Ahmadi, Khazar, et al.
Publicado: (2022)

From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease?
por: de Geus, Eco JC
Publicado: (2010)

Brain activation during cognitive planning in twins discordant or concordant for obsessive–compulsive symptoms
por: den Braber, Anouk, et al.
Publicado: (2010)

Onset of Preclinical Alzheimer Disease in Monozygotic Twins
por: Konijnenberg, Elles, et al.
Publicado: (2021)

Genetic Pathways Underlying Individual Differences in Regular Physical Activity
por: de Geus, Eco J.C.
Publicado: (2023)

The SPECT tracer [(123)I]ADAM binds selectively to serotonin transporters: a double-blind, placebo-controlled study in healthy young men
por: van de Giessen, Elsmarieke, et al.
Publicado: (2010)

Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
por: Shekari, Mahnaz, et al.
Publicado: (2023)

Tau pathology as determinant of changes in atrophy and cerebral blood flow: a multi-modal longitudinal imaging study
por: Visser, Denise, et al.
Publicado: (2023)

Impact of cerebral blood flow and amyloid load on SUVR bias
por: Heeman, Fiona, et al.
Publicado: (2022)

Visual assessment of [(18)F]flutemetamol PET images can detect early amyloid pathology and grade its extent
por: Collij, Lyduine E., et al.
Publicado: (2021)

Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis
por: Collij, Lyduine E., et al.
Publicado: (2022)

ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project
por: Ebenau, Jarith L., et al.
Publicado: (2020)

Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort
por: Ingala, Silvia, et al.
Publicado: (2021)

A multisite analysis of the concordance between visual image interpretation and quantitative analysis of [(18)F]flutemetamol amyloid PET images
por: Bucci, Marco, et al.
Publicado: (2021)

Brain Differences in Adolescents Living With Perinatally Acquired HIV Compared With Adoption Status Matched Controls: A Cross-sectional Study
por: van Genderen, Jason G., et al.
Publicado: (2022)

Assessment of functional shunting in patients with sickle cell disease
por: Afzali-Hashemi, Liza, et al.
Publicado: (2022)

Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study
por: Bader, Ilse, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q32gfkp6bhsjuen02qi1bkbb8j