Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with sepsis in the intensive care unit (Mega-ROX Sepsis)

BACKGROUND: The effect of conservative vs. liberal oxygen therapy on 90-day in-hospital mortality in adults with sepsis receiving unplanned invasive mechanical ventilation in the intensive care unit (ICU) is uncertain. OBJECTIVE: The objective of this study was to summarise the protocol and statisti...

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Detalles Bibliográficos
Autores principales: Young, Paul J., Al-Fares, Abdulrahman, Aryal, Diptesh, Arabi, Yaseen M., Ashraf, Muhammad Sheharyar, Bagshaw, Sean M., Beane, Abigail, de Oliveira Manoel, Airton L., Dullawe, Layoni, Fazla, Fathima, Fujii, Tomoko, Haniffa, Rashan, Hodgson, Carol L., Hunt, Anna, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Landoni, Giovanni, Lawrence, Cassie, Maia, Israel Silva, Mackle, Diane, Mazlan, Mohd Zulfakar, Nichol, Alistair D., Olatunji, Shaanti, Rashan, Aasiyah, Rashan, Sumayyah, Kasza, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581255/
https://www.ncbi.nlm.nih.gov/pubmed/37876605
http://dx.doi.org/10.1016/j.ccrj.2023.04.008

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