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Pathogenetic model of survivin-dependent molecular signalling pathways in tumorigenesis of oral cancer and precursor lesions

BACKGROUND: p53 tumour suppressor gene limits unchecked cellular growth in response to DNA damage, by causing G1 arrest and the activation of apoptosis. Inhibitors of apoptosis include survivin which acts by inhibition of caspases. Survivin has a significant role as a cell cycle modulator and is onl...

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Detalles Bibliográficos
Autores principales: Aggarwal, Dipanshu, Shetty, Devi Charan, Jain, Anshi, Gulati, Nikita, Juneja, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581315/
https://www.ncbi.nlm.nih.gov/pubmed/37854918
http://dx.doi.org/10.4103/jomfp.jomfp_5_23