Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study

This pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with (68)Ga-DOTA-UBI( (29–41)) in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed on Bio...

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Autores principales: Nogueira, Solange Amorim, de Barboza, Marycel F., Dell’Aquila, Adriana M., Santos, Durval C. B, Osawa, Akemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581417/
https://www.ncbi.nlm.nih.gov/pubmed/37756436
http://dx.doi.org/10.1097/RLU.0000000000004866
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author Nogueira, Solange Amorim
de Barboza, Marycel F.
Dell’Aquila, Adriana M.
Santos, Durval C. B
Osawa, Akemi
author_facet Nogueira, Solange Amorim
de Barboza, Marycel F.
Dell’Aquila, Adriana M.
Santos, Durval C. B
Osawa, Akemi
author_sort Nogueira, Solange Amorim
collection PubMed
description This pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with (68)Ga-DOTA-UBI( (29–41)) in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed on Biograph mCT 40 PET/CT scanner (Siemens Healthineers); the image began 45–60 minutes postinjection of the radiotracer (148–260 MBq). This study demonstrated that, in 6 patients in whom the PET/CT was classified as positive for identified infectious foci, confirmed by culture of the secretion sample collected during surgery, only 1 patient in antibiotic therapy was negative.
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spelling pubmed-105814172023-10-18 Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study Nogueira, Solange Amorim de Barboza, Marycel F. Dell’Aquila, Adriana M. Santos, Durval C. B Osawa, Akemi Clin Nucl Med Interesting Images This pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with (68)Ga-DOTA-UBI( (29–41)) in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed on Biograph mCT 40 PET/CT scanner (Siemens Healthineers); the image began 45–60 minutes postinjection of the radiotracer (148–260 MBq). This study demonstrated that, in 6 patients in whom the PET/CT was classified as positive for identified infectious foci, confirmed by culture of the secretion sample collected during surgery, only 1 patient in antibiotic therapy was negative. Lippincott Williams & Wilkins 2023-11 2023-09-21 /pmc/articles/PMC10581417/ /pubmed/37756436 http://dx.doi.org/10.1097/RLU.0000000000004866 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Interesting Images
Nogueira, Solange Amorim
de Barboza, Marycel F.
Dell’Aquila, Adriana M.
Santos, Durval C. B
Osawa, Akemi
Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title_full Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title_fullStr Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title_full_unstemmed Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title_short Could (68)Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study
title_sort could (68)ga-dota-ubi-29-41 help identify chronic osteomyelitis on pet/ct images? a pilot study
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581417/
https://www.ncbi.nlm.nih.gov/pubmed/37756436
http://dx.doi.org/10.1097/RLU.0000000000004866
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