Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients

BACKGROUND AND AIMS: HBV infection is restricted to the liver, where it drives exhaustion of virus-specific T and B cells and pathogenesis through dysregulation of intrahepatic immunity. Our understanding of liver-specific events related to viral control and liver damage has relied almost solely on...

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Detalles Bibliográficos
Autores principales: Genshaft, Alex S., Subudhi, Sonu, Keo, Arlin, Sanchez Vasquez, Juan Diego, Conceição-Neto, Nádia, Mahamed, Deeqa, Boeijen, Lauke L., Alatrakchi, Nadia, Oetheimer, Chris, Vilme, Mike, Drake, Riley, Fleming, Ira, Tran, Nancy, Tzouanas, Constantine, Joseph-Chazan, Jasmin, Arreola Villanueva, Martin, van de Werken, Harmen J. G., van Oord, Gertine W., Groothuismink, Zwier M. A., Beudeker, Boris J., Osmani, Zgjim, Nkongolo, Shirin, Mehrotra, Aman, Spittaels, Kurt, Feld, Jordan, Chung, Raymond T., de Knegt, Robert J., Janssen, Harry L. A., Aerssens, Jeroen, Bollekens, Jacques, Hacohen, Nir, Lauer, Georg M., Boonstra, Andre, Shalek, Alex K., Gehring, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Viral Hepatitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581444/
https://www.ncbi.nlm.nih.gov/pubmed/37158243
http://dx.doi.org/10.1097/HEP.0000000000000438

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