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Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis
AIM: In vivo and in vitro toxicity tests of JointAlive(®) were studied in animal models to support the safe use of JointAlive(®) as a drug for knee osteoarthritis treatment. METHODS: The acute toxicity study in Sprague Dawley (SD) rats was conducted at a 20 g/kg bw/day dose of JointAlive(®). For 13-...
Autores principales: | Wang, Yuanyuan, Li, Li, Mu, Yanling, Wang, Shanglong, Li, Xin, Zong, Jiancheng, Zou, Shengcan, Liu, Zimin, Gao, Dehai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581469/ https://www.ncbi.nlm.nih.gov/pubmed/37847690 http://dx.doi.org/10.1371/journal.pone.0292937 |
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