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Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya

BACKGROUND: Late-stage blinding sequalae of trachoma such as trachomatous trichiasis (TT) typically take decades to develop and often do so in the absence of ongoing ocular Chlamydia trachomatis infection. This suggests that most TT risk accumulates in early life; as a result, population-level TT in...

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Autores principales: Ilako, D, Barasa, E, Gichangi, M, Mwatha, S, Watitu, T, Bore, J, Rajamani, A, Butcher, R, Flueckiger, RM, Bakhtiari, A, Willis, R, Solomon, AW, Harding-Esch, EM, Matendechero, SH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581664/
https://www.ncbi.nlm.nih.gov/pubmed/35037814
http://dx.doi.org/10.1080/09286586.2021.1986549
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author Ilako, D
Barasa, E
Gichangi, M
Mwatha, S
Watitu, T
Bore, J
Rajamani, A
Butcher, R
Flueckiger, RM
Bakhtiari, A
Willis, R
Solomon, AW
Harding-Esch, EM
Matendechero, SH
author_facet Ilako, D
Barasa, E
Gichangi, M
Mwatha, S
Watitu, T
Bore, J
Rajamani, A
Butcher, R
Flueckiger, RM
Bakhtiari, A
Willis, R
Solomon, AW
Harding-Esch, EM
Matendechero, SH
author_sort Ilako, D
collection PubMed
description BACKGROUND: Late-stage blinding sequalae of trachoma such as trachomatous trichiasis (TT) typically take decades to develop and often do so in the absence of ongoing ocular Chlamydia trachomatis infection. This suggests that most TT risk accumulates in early life; as a result, population-level TT incidence and prevalence can remain high years after C. trachomatis transmission among children has decreased. In Embu and Kitui counties, Kenya, the prevalence of trachomatous inflammation – follicular is low in children. In this survey, we set out to determine the prevalence of TT in ten evaluation units (EUs) in these counties. METHODS: We undertook ten cross-sectional prevalence surveys for TT. In each EU, people aged ≥15 years were selected by a two-stage cluster sampling method and examined for TT. Those with TT were asked questions on whether they had been offered management for it. Prevalence was adjusted to the underlying age and gender structure of the population. RESULTS: A total of 18,987 people aged ≥15 years were examined. Per EU, the median number of examined participants was 1,656 (range: 1,451 − 3,016) and median response rate was 86% (range: 81 − 95%). The prevalence of TT unknown to the health system in people aged ≥15 years was above the threshold for elimination (≥0.2%) in all ten EUs studied (range: 0.2–0.7%). TT was significantly more common in older than younger individuals and in women than in men. DISCUSSION: Provision of surgical services should be strengthened in Embu and Kitui counties of Kenya to achieve the World Health Organization threshold for eliminating TT as a public health problem.
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spelling pubmed-105816642023-10-18 Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya Ilako, D Barasa, E Gichangi, M Mwatha, S Watitu, T Bore, J Rajamani, A Butcher, R Flueckiger, RM Bakhtiari, A Willis, R Solomon, AW Harding-Esch, EM Matendechero, SH Ophthalmic Epidemiol Research Article BACKGROUND: Late-stage blinding sequalae of trachoma such as trachomatous trichiasis (TT) typically take decades to develop and often do so in the absence of ongoing ocular Chlamydia trachomatis infection. This suggests that most TT risk accumulates in early life; as a result, population-level TT incidence and prevalence can remain high years after C. trachomatis transmission among children has decreased. In Embu and Kitui counties, Kenya, the prevalence of trachomatous inflammation – follicular is low in children. In this survey, we set out to determine the prevalence of TT in ten evaluation units (EUs) in these counties. METHODS: We undertook ten cross-sectional prevalence surveys for TT. In each EU, people aged ≥15 years were selected by a two-stage cluster sampling method and examined for TT. Those with TT were asked questions on whether they had been offered management for it. Prevalence was adjusted to the underlying age and gender structure of the population. RESULTS: A total of 18,987 people aged ≥15 years were examined. Per EU, the median number of examined participants was 1,656 (range: 1,451 − 3,016) and median response rate was 86% (range: 81 − 95%). The prevalence of TT unknown to the health system in people aged ≥15 years was above the threshold for elimination (≥0.2%) in all ten EUs studied (range: 0.2–0.7%). TT was significantly more common in older than younger individuals and in women than in men. DISCUSSION: Provision of surgical services should be strengthened in Embu and Kitui counties of Kenya to achieve the World Health Organization threshold for eliminating TT as a public health problem. Taylor & Francis 2022-01-17 /pmc/articles/PMC10581664/ /pubmed/35037814 http://dx.doi.org/10.1080/09286586.2021.1986549 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Research Article
Ilako, D
Barasa, E
Gichangi, M
Mwatha, S
Watitu, T
Bore, J
Rajamani, A
Butcher, R
Flueckiger, RM
Bakhtiari, A
Willis, R
Solomon, AW
Harding-Esch, EM
Matendechero, SH
Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title_full Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title_fullStr Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title_full_unstemmed Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title_short Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
title_sort prevalence of trachomatous trichiasis in ten evaluation units of embu and kitui counties, kenya
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581664/
https://www.ncbi.nlm.nih.gov/pubmed/35037814
http://dx.doi.org/10.1080/09286586.2021.1986549
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